Mark 16:20
Then the disciples went out and preached everywhere, and the Lord worked with them and confirmed his word by the signs that accompanied it — the disciples' preaching everywhere is the opening of the mission to all nations that the Great Commission specified. The Lord working with them and confirming his word by signs is the pattern of the book of Acts — the word proclaimed and accompanied by signs that attest its divine origin. The Gospel that began with the beginning (1:1) ends with the disciples going everywhere — the ongoing story of the kingdom's spread through proclamation and signs.