“When Jesus therefore had received the vinegar, he said, It is finished: and he bowed his head, and gave up the ghost.”
John 19:30 — Greek Interlinear
Church Fathers on John 19:30
After this Jesus knowing that all things were now accomplished; i.e. knowing the prophecy in the Psalms, And when I was thirsty, they gave me vinegar to drink, said, I thirst: As if to say, you have not done all give me yourselves: for the Jews were themselves vinegar having degenerated from the wine of the Patriarchs and the Prophets. Now there was a vessel full of vinegar: they had drunk from the wickedness of the world, as from a full vessel, and their heart was deceitful,…
They were not softened at all by what they saw, but were the more enraged, and gave Him the cup to drink, as they did to criminals, i.e. with a hyssop.
Some say that the hyssop is put here for reed, its leaves being like a reed.